Abstract With the increasing aging of mankind worldwide, aging study has become very important. Senescent cells are generally created in vitro via prolonged division in culture since replicative senescence is defined as a state in which normal somatic cells […]
Abstract 1. Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in several PD animal models. 2. IDUNA (RNF146) is […]
Abstract Olfactory receptors (ORs) are 7-transmembrane G-protein coupled receptors which, when expressed in the olfactory epithelium, play a pivotal role in the sense of smell. However, recent studies have highlighted important roles played by ORs in a variety of other […]
Abstract Type 2 diabetes(T2D) is caused by a complex interplay between genetic and environmental factors and likely comprises heterogeneous disorders with common phenotype of chronic hyperglycemia. Current understanding of pathogenesis and natural history of T2D are mostly based on studies […]
Abstract Modern technology-driven society largely relies on energy storage systems or electric vehicles for eco-friendly transportation and the use of high technology devices. Lithium rechargeable batteries are the most promising power sources because of its high energy density but still […]
Abstract It is generally known that one third of people between the age of 65 and 74 years have some degree of hearing loss, and half of people older than 75 have similar hearing difficulty. Age-related hearing loss, also known […]
Abstract Extensive research efforts have been devoted to the development of alternative battery chemistry to replace the current technology of lithium-ion batteries(LIBs). Here, we demonstrate that the [Li, Na]-SO2 battery chemistry, already established 30 years ago, has considerable potential to […]
Abstract Li ion batteries (LIBs) are one of the most successful energy storage devices for portable electronics application, electrical vehicles, and utility grids. However, there are still strong needs for higher energy density and lower price materials than what the […]
Abstract Dose, L. Zhang, J. Blauwkamp, W. Lu, and C. S. Johnson* Silicon containing anodes employed in Li-ion cells are known to dramatically boost the energy density of a full LIB battery by providing a high intrinsic capacity via LixSi […]
Abstract Olfactory receptors (ORs) are 7-transmembrane G-protein coupled receptors which, when expressed in the olfactory epithelium, play a pivotal role in the sense of smell. However, recent studies have highlighted important roles played by ORs in a variety of other […]