Recent developments in nano/micro technology have made it possible to construct small-scale bio-analytical devices for the analysis of biological markers such as nucleic acids, proteins, small molecules, and cells.
- Circulating tumor cells (CTCs) are highly correlated with the invasive behavior of cancer, so their isolations and quantifications are important for biomedical applications such as cancer prognosis and measuring the responses to drug treatments. In this paper, we present the development of a microfluidic device for the separation of CTCs from blood cells based on the physical properties of cells.
- Blood hemoglobin is an important diagnostic parameter in measuring overall health. We presents a new method for determining the hemoglobin concentration of erythrocytes by measuring temperature increases of the heme group when cells are heated by a 532 nm wavelength laser.
- Rapid, real-time detection of pathogenic microorganisms is an emerging and quickly evolving field of research, especially with regard to microorganisms that pose a major threat to public health. Herein, a new method that uses bioimpedance and solid culture medium for the real-time monitoring of bacterial growth is introduced.
- Although biochip technology for the diagnosis of severe physiological diseases (e.g., cancer, diabetes, and cardiovascular disease) has been extensively studied, biochips for the monitoring of human emotions such as stress, fear, depression, and sorrow have not yet been introduced, and the development of such a biochip is in its infancy. In this paper we discuss the potential importance of biochip technology in which human emotion can be precisely measured in real time using body fluids such as blood, saliva, urine, or sweat. We call these biochips emotion-on-a-chip (EOC).
- 1998-2001, Ph.D., Department of Biochemistry, University of Cambridge, UK
- 1993-1995, MSc. Department of Biological Sciences, KAIST, Korea
- 1988-1993, B.S., Department of Biotechnology, KAIST, Korea
- 2010-Present, Professor Yonsei University, Korea
- 2006-2010, Associate Professor Yonsei Univeristy, Korea
- 2004-2006, Assistant Professor Yonsei University, Korea
- 2001-2004, Research Fellow, Univ. of Cambridge, UK