Robotic Manipulation of Cells from Clinical Samples

Yu Sun
Yu Sun
Univ. of Toronto, Canada
10:40~11:25, November 21st, 2014

Abstract :

Robotic cell surgery and automated biophysical characterization of cells enable new frontiers in science and have tangible clinical relevance. Due to the small sizes of cells and sub-cellular structures and due to their heterogeneity in a clinical sample, automated manipulation and characterization of single cells at a high speed is challenging. This presentation will introduce our robotic cell manipulation technologies. Hardware platforms (robotic systems and micro devices) and techniques such as cell immobilization, visual servo control, and mechanical characterization of cells will be presented. Example work with collaborating hospitals on robotic manipulation of sperm, oocytes, and urine cells will be discussed. System performance and applications to molecule testing, clinical cell surgery, and bladder cancer detection will be highlighted.


Research Areas

Manipulation and characterization of biological cells, molecules, and nanomaterials; design and microfabrication of bioMEMS, sensors, actuators, and microfluidic devices; micro-nano robotic manipulation under optical and electron microscopy.


Awards and Honors

  • 2014 : MIE Teaching Award, University of Toronto
  • 2014 : Fellow, Canadian Academy of Engineering (CAE)
  • 2014 : UofT’s Connaught Innovation Award
  • 2013 : NSERC E.W.R. Steacie Memorial Fellowship
  • 2013 : Fellow, American Society of Mechanical Engineers
  • 2013 : Fellow, Engineering Institute of Canada (EIC)
  • 2013 : UofT’s Connaught Innovation Award
  • 2012 : UofT’s Connaught Innovation Award
  • 2011 : UofT’s Inventor of the Year Award (First Prize)
  • 2011 : UofT’s Connaught Innovation Award
  • 2010 : IEEE Robotics and Automation Society Academic Early Career Award “for contributions to enabling microrobotic and MEMS technologies for automated cell manipulaiton and characterization in cell biology and clinical applications”
  • 2009 : First Prize for Technical Achievement by the American Society for Reproductive Medicine (ASRM)