Brain Plasticity from Synapse to Cognition

Hierarchical processing in the brain

Abstract : Language processing is a trait of human species. The knowledge about its neurobiological basis has been increased considerably over the past decades. In patient studies, various lesions have been known to be related to specific language deficits. In the […]

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Novel mechanisms regulating NMDAR-dependent synaptic plasticity: anion channels and presynaptic NMDARs

Abstract : Presynaptic glutamate released by the certain type of neural activities can activate N-methyl-D-aspartate subtype of glutamate receptors (NMDARs) in postsynaptic dendrites, leading to induction of long-term potentiation (LTP) at many excitatory synapses. However, recent studies have also suggested possible […]

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Forebrain-specific roles of phospholipase Cγ1 for normal and pathological behavior

Abstract : Manic episodes are one of the major diagnostic symptoms in a spectrum of neuropsychiatric disorders that include schizophrenia, obsessive-compulsive disorder, and bipolar disorder (BD). Despite a possible association between BD and the gene encoding phospholipase Cγ1 (PLCG1), its etiological […]

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Brain-Inspired Artificial Neural Network: A Neurobiologist’s View On Research Innovation: A Personal View

Abstract : In this talk, I will discuss the nature of innovation in research, drawing mainly from my experience as a neurobiologist. I will address six aspects of innovative research – novelty, significance, continuity, completeness, uniqueness, and timeliness – and these […]

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Language, memory, and brain: A cognitive neuroscience perspective on first and second language

Abstract : Increasing evidence suggests that language learning, knowledge, and use crucially depend on two learning and memory systems in the brain: declarative memory and procedural memory. These systems, which also exist in other vertebrate species, appear to have been co-opted […]

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