Brain Science

The synaptic signaling scaffold GIT1 and attention deficit hyperactivity disorder

Abstract : Growing number of synaptic proteins are being associated with various brain diseases including schizophrenia, autism, and attention deficit hyperactivity disorder (ADHD). ADHD is a psychiatric disorder that affects ~5% of school-aged children; however, the mechanisms underlying ADHD remain […]

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How the Brain makes Sense of Scents

Abstract : The olfactory system is capable of recognizing and discriminating between a staggering number and variety of odorants, which are primarily small organic molecules. It performs this task over many orders of concentration and with complex blends of chemicals […]

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Molecular Mechanisms of Learning and Memory

Abstract : One of the great challenges in the 21st century is to understand the biology of mental activity or mind. One of key components in the mind is learning and memory. Learning is the process by which we obtain […]

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Food for Thought: Fatty Acid Metabolism, Signaling and the Brain

Abstract : A role for fatty acid metabolism in the regulation of energy balance has been considered only recently, and generated the hypothesis that pharmacological alteration of fatty acid flux might affect food intake. Among the enzymes that facilitate fatty […]

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Lipidomics, New Tools and Applications

Abstract : Once viewed simply as a reservoir for carbon storage, lipids are no longer cast as bystanders in the drama of biological systems. The emerging field of lipidomics is driven by technology, most notably mass spectrometry, but also by […]

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Phosphoinositide lipid metabolism regulates cells and ion channels

Abstract : Phosphoinositides (PIs) are rare phospholipids in cell membranes. The simplest form, phosphatidylinositol, is the most abundant of the family. It can be phosphorylated by specific cytoplasmic lipid kinases and dephosphorylated by lipid phosphatases on the 3, 4, and […]

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