Abstract Optical stimulation technology has become an attractive neuromodulation technique as it has potential benefit to provide high spatio-temporal resolution in controlling individual neurons. In addition, cell targeting is also possible by optogentics or functionalized nanoparticles. In this presentation, I […]
Abstract Due to recent advances in microfabricated cell culture technology, the ability to realistically simulate important biological steps in disease models including cancer has dramatically improved. In particular, the capability to reproduce the niche of cancers in stem cells and […]
Abstract Recent developments in nano/micro technology have made it possible to construct small-scale bio-analytical devices for the analysis of biological markers such as nucleic acids, proteins, small molecules, and cells. Circulating tumor cells (CTCs) are highly correlated with the invasive […]
Abstract Living materials show superior functions to the artificial ones in terms of the ability to recognize/produce biomolecules. For example, cells (in particular membrane proteins) achieve highly-sensitive and selective detection of several chemicals at the molecular level; they can even […]
Abstract Of the new industries of the Fourth Industrial Revolution including artificial intelligence(AI), robot, virtual reality (VR), internet of things (IoT), bio, three-dimension (3D) and printing, scientists expects bio-industry, which is closely related to productivity, health and welfare of human […]
Abstract With the increasing aging of mankind worldwide, aging study has become very important. Senescent cells are generally created in vitro via prolonged division in culture since replicative senescence is defined as a state in which normal somatic cells […]
Abstract 1. Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in several PD animal models. 2. IDUNA (RNF146) is […]
Abstract Olfactory receptors (ORs) are 7-transmembrane G-protein coupled receptors which, when expressed in the olfactory epithelium, play a pivotal role in the sense of smell. However, recent studies have highlighted important roles played by ORs in a variety of other […]
Abstract Type 2 diabetes(T2D) is caused by a complex interplay between genetic and environmental factors and likely comprises heterogeneous disorders with common phenotype of chronic hyperglycemia. Current understanding of pathogenesis and natural history of T2D are mostly based on studies […]
Abstract It is generally known that one third of people between the age of 65 and 74 years have some degree of hearing loss, and half of people older than 75 have similar hearing difficulty. Age-related hearing loss, also known […]